Chinese medicine can inhibit enzymes non-diabetes glycated proteins, cell activity may be material expression of sugar rehabilitation treatment of early diabetic nephropathy mechanism, the ultimate reducing kidney morphology and renal injury.
By the famous Chinese experts, the first hospital in Tianjin, Zhang Bolin, director of physicians chaired by the State Fund for Nature issue "sugar rehabilitation in the early non-diabetic nephropathy of protein glycosylation, the impact of physical activity," recently passed by the experts in Tianjin Science and Technology Commission Identification of.
From the subject of non-diabetic glycated proteins, cell activity pathological material expression of two important aspects proceed, the establishment of Aminoguanidine, benazepril two western medicine control group, the rehabilitation of sugar in diabetic rats lowered renal cortex of non-protein glycosylation The end product of the effect of age and aminoguanidine a lower renal cortex of transforming growth factor - 1 and the effect of a benazepril, while reducing the ICAM-1, ET-1 and other material expression of cell activity And reduce the glomerular extracellular matrix components (such as iv-c, fn) accumulation and kidney damage morphology, showed that inhibition of non-diabetic glycated proteins, cell activity may be material expression of sugar rehabilitation treatment of early diabetic kidney The mechanism of disease and ultimately reduce the morphology of the kidney and renal dysfunction.
Identification of experts believe that the establishment of the project so that the two drugs on strict control, in-depth topic, the incidence of diabetic nephropathy from different segments of a systematic mechanism of traditional Chinese medicine treatment is the leading domestic sugar rehabilitation of the multi-target performance of the rich Chinese medicine treatment of diabetic nephropathy theoretical basis
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(Internship Editor: Wu Wei Qi)